Lab News

October 2018: Excited that our SWBIO DTP studentship has been selected for advertisement. This project is a collaboration between my lab (ubiquitin signalling), Prof Christiane Berger-Schaffitzel (University of Bristol, Cryo-EM), and Prof Jean Van Den Elsen (University of Bath, Biophysics), starting October 2019.

The deadline is December 3rd 2019.

September 2018: Welcome to Nico Scholz,  GW4 MRC BioMed PhD student in my laboratory, in collaboration with Dr Kathreena Kurian (Bristol) and Dr Florian Siebzehnrubl (European Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University).

September 2018: Great time in Arosa, giving a talk at the EMBO Membrane contact sites in health and disease workshop. Great community and exciting science!

August 2018: Farewell to James Breakes MSc Bioscience student who did a fantastic job expressing/purifying proteins this summer.

July 2018: Excited to have been selected to participate and give a talk at EMBO Membrane Contact Sites in Health and Disease ( this September in Arosa, Switzerland.

July 2018: Both Sarah (Final year PhD student) and I will give talks at the 12th Mammalian Genetic, Development and Disease meeting in Bristol (sponsored by the Genetics Society).

June 2018: Welcome to James Breakes, our new MSc BioScience trainee in protein expression and purification.

June 2018: Excited to present our work on the evolution of E3 ligases at the South West Structural Biology Consortium in Exeter.

April 2018: Congrats to Dr Natalie Vaughan first PhD student from the lab, who passed her viva. Thank you to Prof Judy Coulson for examining.

April 2018: Welcome to Ni Yang and Shikha Kataria, MRes student in BioScience.

March 2018: Good meeting with Nico Scholz and his other supervisors Dr Kathreena Kurian and Dr Florian Siebzehnrubl to discuss his project: “Targeting the Ubiquitin-Proteasome System in Glioblastoma”.

March 2018: Well done to Natalie for submitting her thesis.

Natalie submission

March 2018: Yes, March! Lee and I braving the snow storm to finish our protein purification.

Lee & Julien braving the snow storm

February 2018: Look out for the Frontiers In Physiology Special topic on E3 Ubiquitin Ligases: From Structure to Physiology.

February 2018: Welcome to Sophie Foggin, Final year Nat Sci student.

February 2018: A big thank you to the organizers and attendees for making the COST Proteostasis a success.

Cost group in Athens

February 2018: Nice to be in Athens for a few days!

February 2018: Great proteasome meeting near Munich!

Muncih conf

February 2018: Excited to give talks at the Proteasome Hub in Munich ( and the COST Proteostasis meeting in Athens (

January 2018: Thank you to our ARUK Network for a pilot grant.

January 2018: Excellent news: Our GW4 MRC Biomed Studentship has been selected, and our student Niko Scholtz will start in October 2018.

October 2017: Wellcome to Lee Harris who joins us to start a PhD funded by Alzheimer’s Research UK on mutant ubiquitin in the brain.

October 2017: Wellcome to Emma Bunting and Nicolas Picard Garcia, Nat Sci Undergraduate project students.

September: BSc (Hons) Biochemistry Tutee Kim Owen shadows PhD student Sarah  for a week. Welcome Kim.


August 2017: Farewell to Karlo and Austin who have finished their MSc in BioScience project on E3 ubiquitin ligases.

August 2017: Our project “Targeting the Ubiquitin-Proteasome System in Glioblastoma” in collaboration with Dr Kathreen Kurian (Uni of Bristol), Dr Florian Siebzehnrubl and Professor Matt Smalley (Cardiff Uni) has been selected for advertisement.

Please click MRC GW4 BioMed PhD studentship_Licchesi Lab for details. Advert also available on

Details of the position available here. Student applications will open on 24th September and close on Friday 24th November 2017.

July 2017: Julien joins the Biochemical Society Theme panel for Research area IV, Cells.

July 2017: The final published version of your Full Paper “Activity-Based Probes for HECT E3 ubiquitin ligases” by Robert Byrne is available online.

June 2017: Off to the Biochemical society conference: Deubiquintinases – from structure to physiology.

Second year PhD student presents her work on “a novel neuronal E3 ubiquitin ligase at the GW4 early career neuroscientists day 2017 in Cardiff.

June 2017: Thank you to the Bath Alumni for funding our project “A potential new target for treating brain tumours”.

May 2017: Farewell to final year project students Luke Patisson, Emma Thatcher, Ruby Coates, Samantha Haque, Bethany Gray and Helen Middleton.

Article in the Biomedical Scientist on Natalie’s STEM4 BRITAIN award.

April 2017: First paper from the lab.!Placement student Robert Byrne’s paper “Activity-Based Probes for HECT E3 ubiquitin ligases” is accepted in ChemBiochem.

April 2017: 3-year Alzheimer’s Research PhD studentship advertised

Click here for details on ARUK PhD studentship – Deadline for application May 19th 2017

March 2017: Sir Paul Nurse delivers the 2017 PGBIO Inspirational Lecture. Excellent day! Thank you Natalie for organizing and hosting.

March 2017: 38-39_bs_the_stem_for_britain_award_winners(1)


February 2017: We welcome our 6 undergraduates for this semester: Ruby, Emma, Sam, Luke, Beth and Helen.

February 2017. Great news! Harry Horsnell, lab alumni, is recruited for a PhD in at the MRC-Laboratory of Cell and Molecular Biology in London.

January 2017: Great news! Our Alzheimer’s Research UK PhD studentship has been selected for funding.

January 2017: Well done to Natalie who has been selected to attend the STEM4 Britain competition at the London House of Parliament in March. Great achievement. Well done Natalie!

January 2017: Really sad to report the passing of our friend/colleague/lab made Jim Caunt. Jim was such a wonderful colleague, dedicated teacher and excellent scientist, he will be hugely missed. RIP Jim.

December 2016: Off to attend the last Oxford Ubiquitin Club of 2016;)

December 2016: Off to Oxford with second year PhD student Sarah to attend the MITOX Mitochondrial meeting. Sarah will present a poster on protein ubiquitination and mitochondrial metabolism. Project has just started but data look encouraging.

December 2016: We are hosting collaborator Catherine Lisdon for a seminar and to discuss data on Natalie’s project. Great talk entitled “Ubiquitin-mediated pathways in cell division”.

December. Great news! Ioanna Stefani, lab alumni, is recruited for a PhD in Lausanne.

November 2016: Great news! Natalie won Best Poster at the COST-Proteostasis meeting, well done Natalie!


November 2016: Off to Lisbon for the COST-Proteostasis Meeting, can’t wait to present our two posters!

September 2016: Welcome to 2nd year Biochemistry tutee Charlie Nutall is shadowing PhD student Natalie for a week.


August 2016: Natalie is off to Catherine Lindon’s lab, Cambridge, to carry out time lapse microscopy.

August 2016: Farewell to Res students Laia and Ioanna.

July 2016: Farewell to Rob Byrne, placement student, all the best for your final year @ Cardiff.

July 2016: visit of our lab by Alzheimer’s Research UK and local MP Ben Howlett.

June 2016: Science is international!

Cyprus, English, French, English, Belgium.

June 2016: Oxford Ubiquitin Club, seminar by Natalie Vaughan.

June 2016: Congrats to Harry Hornsell who wins the Broabent prize for for outstanding achievement throughout the course of the degree.


June 2015: Congrats to Harry Horsnell and Michael Hugues two oustanding final year project students in my lab who graduated with a 1st class BSc (hons) Biochemistry.

May 2015: Alzheimer’s’ Research UK Network Grant awarded.

May 2016: Oxford Ubiquitin Club, seminar by Robert Byrne.

March 2016: Welcome to MRes students Laia and Ioanna.

March 2016: Bath half marathon. Julien raises £360.87 for the Alzheimer’s Society.


November 2015: Alzheimer’s’ Research UK Network Meeting “Alzheimer’s Disease: Beyond the Gene”, Bristol. Seminar by Julien Licchesi.

October 2015: Sarah Jasem (Kuwaiti scholarship) starts her PhD on “Ubiquitin, brain cells and metabolism”.

October 2015: Natalie Vaughan participate in the Practical course on ubiquitin and ubiquitin-like proteins, Frankfurt Germany.

September 2015: Robert Bryne (Cardiff University) starts his placement om the ‘Biochemical characterization of E3 ligases”.

March 2015: Alzheimer’s’ Research UK Conference, Manchester.

April 2015: Oxford Ubiquitin Club, Seminar by Julien Licchesi.

February 2015: Alzheimer’s’ Research UK pilot grant awarded.

Julien Licchesi (dark hair) and Rob Williams are carrying out research into the causes of Alzheimers.

October 2014: Natalie Vaughan starts her PhD on ‘Ubiquitin and the cell cycle’.

July 2014: MRC- Laboratory of Molecular Biology Alumni Symposium 2014: Molecular Biology @ 50 and beyond.


November 2014: COST-Proteostasis meeting, Valencia.


February 2014: Royal Society Grant awarded.

November 2014: Cancer Research @ Bath Seminar by Julien Licchesi, University of Bath.

November 2014: Cell & Developmental Biology Seminar by Julien Licchesi, University of Bath.

June 2013: Start of Lectureship at University of Bath.