Peer-reviewed publications

  • Byrne R, Mund T , Licchesi JDF. Activity-Based Probes for HECT E3 Ubiquitin Ligases. Chembiochem. 2017 Jul 18;18(14):1415-1427. doi: 10.1002/cbic.201700006. Epub 2017 Jun 28. Click here for Open Access article.
  • Yu Y, Yan W, Liu X, Jia Y, Cao B, Yu Y, Lv Y, Brock MV, Herman JG, Licchesi J, Yang Y, Guo M. DACT2 is frequently methylated in human gastric cancer and methylation of DACT2 activated Wnt signaling. Am J Cancer Res. 2014 Nov 19;4(6):710-24. Click here for paper.
  • Wrangle J, Machida EO, Danilova L, Hulbert A, Franco N, Zhang W, Glöckner SC, Tessema M, Van Neste L, Easwaran H, Schuebel KE, Licchesi J, Hooker CM, Ahuja N, Amano J, Belinsky SA, Baylin SB, Herman JG, Brock MV. Functional identification of cancer-specific methylation of CDO1, HOXA9, and TAC1 for the diagnosis of lung cancer. Clin Cancer Res. 2014 Apr 1;20(7):1856-64. Click here for paper.
  • Zhang X, Yang Y, Liu X, Herman JG, Brock MV, Licchesi JD, Yue W, Pei X, Guo M. Epigenetic regulation of the Wnt signaling inhibitor DACT2 in human hepatocellular carcinoma. Epigenetics. 2013 Feb 28;8(4). Click here for paper.
  • Licchesi JDF, Mieszczanek J, Mevissen TET, Rutherford TJ, Akutsu M, Virdee S, El Oualid F, Chin JW, Ovaa H, Bienz M and Komander D. The ubiquitin-binding ankyrin repeat module of TRABID is critical for its ability to cleave Lys29- and Lys33-linked ubiquitin. Nature Structural & Molecular Biology, 2011 Dec 11;19(1):62-71. Click here for paper.
  • Research highlight in Nature Reviews Molecular cell Biology. 13, 64-65 (February 2012). Click here for paper.
  • Licchesi JDF*, Van Neste L, Tiwari VK, Cope L, Lin X, Baylin SB, Herman JG. Transcriptional regulation of Wnt inhibitory factor-1 by Miz-1/c-Myc. Oncogene 2010 Nov 4;29(44):5923-34. Epub 2010 Aug 9. (*co-corresponding author). Click here for paper.
  • Komander D, Reyes-Turcu F, Licchesi JDF, Odenwaelder P, Wilkinson KD, Barford D. Molecular discrimination of structurally equivalent lys63-linked and linear polyubiquitin chains. EMBO Reports. 2009 May;10(5):466-73. Click here for paper.
  • Tiwari VK, McGarvey KM, Licchesi, JDF, Ohm JE,  Herman JG, Schübeler D, Baylin SB. .. PcG proteins, DNA methylation and Gene Repression by Chromatin Looping. PLoS Biol. 2008 Dec 2;6(12):2911-27. Click here for paper.
  • Licchesi JDF, Westra WH, Hooker CM, Herman JG.. Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung. Clinical Cancer Res. 2008 May 1;14(9):2570-8. Click here for paper.
  • Licchesi JDF, Westra WH, Hooker CM, Machida EO, Baylin SB, Herman JG . Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. Carcinogenesis. 2008 May;29(5):895-904. Click here for paper.
  • Benavides F, Zamisch M, Flores M, Campbell MR, Andrew SE, Angel JM, Licchesi JDF, Sternik G, Richie ER, Conti CJ.. Application of inter-simple sequence repeat PCR to mouse models: assessment of genetic alterations in carcinogenesis. Genes Chromosomes Cancer. 2002 Dec;35(4):299-310.

Book Chapters

  • Licchesi JDF and Herman JG. Methylation-Specific PCR. DNA methylation protocols. Methods in Molecular Biology Series. Humana Press. 2009;507:305-23. Click here for paper.